Frederick, Md

Trammell Crow Company, Principal Real Estate Investors Announce 500,000-SF Life Science Campus in Maryland

April 13, 2022


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Elise Maguire Ferrara

U.S. Communications and Media Manager

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Trammell Crow Company (TCC), the nation’s largest commercial real estate developer, and Principal Real Estate Investors, a top-10 global real estate asset manager , announced plans for Jefferson Technology Park, a 500,000-square-foot life science campus in Frederick, MD. The campus will include two 100,000-square-foot laboratory, research, and biodiscovery buildings, connected by a 10,000-square-foot amenity hub, and two 145,000-square-foot clean-room production buildings. Construction will begin in September and completion is anticipated for late 2023.  

At completion, Jefferson Tech Park will deliver the Frederick market a much-needed life science ecosystem that will foster innovation, collaboration, and discovery. This best-in-class campus will include R&D laboratory space capable of meeting the full spectrum of Bio Safety Levels (BSL) categorical designations, along with Good Manufacturing Practice (GMP) clean-room production space. The campus will feature a comprehensive offering of on-campus amenities intended to create a one-of-a-kind user experience, enjoyed by employees, their families, and visitors. Jefferson Tech Park will be the premier biodiscovery campus in Frederick, promoting integrated research and biomanufacturing in one dynamic setting.

The two three-story laboratory buildings will each benefit from four sides of light and air, allowing for daylighting of interior spaces, which will feature a best-in-class column layout that provides a nearly column-free workspace and floor-to-floor heights ranging from 16’ to 18’. Jefferson Technology Park will also include two single-story clean-room production buildings, which will have typical bay sizing across floorplates and will feature ceiling heights of 36’.

The shared amenity hub at the campus will include front-of-house spaces, including a coworking space, conferencing facilities, a fitness center with a locker room and a café. This building will also house the campus’ on-site building management, its shipping and receiving space and hazardous material storage. Additional amenities at Jefferson Technology Park will include abundant green space, outdoor seating and gathering areas, fitness and walking trails, ample employee parking, and loading docks.  

“Jefferson Technology Park has been envisioned as a comprehensive life science campus that can deliver state-of-the-art laboratory and clean-room production space to the I-270 marketplace,” said Eric Fischer, Managing Director with TCC’s MidAtlantic office. “The campus will feature a comprehensive set of on-site amenities intended to create a best-in-class experience for employees and visitors. Once complete, Jefferson Technology Park will be the premier life science campus in the area, allowing for integrated research and manufacturing in one dynamic setting.”

“Jefferson Technology Park is a unique life science campus development opportunity that will further reinforce Frederick as the northern anchor of the I-270 Life Sciences Corridor. Jefferson Tech will be an exciting addition to the market, and we are looking forward to continuing our strong joint venture partnership with Trammell Crow to deliver this project,” said Rob Klinkner, Managing Director of the eastern states region for Principal Real Estate Investors. 

Frank C. Graybeal and Kevin Reap of CBRE are handling the marketing and the leasing at the development. 

“To finally have institution sponsorship with the knowledge, understanding and capital to meet the growing demands for quality life science product in the Upper I-270 Corridor’s Frederick Market is long overdue,” said Graybeal. “Not just a one-off building opportunity development, Trammell Crow’s Labs at Jefferson Tech Park will reflect a true life sciences ecosystem in support for R&D and biomanufacturing product that is desperately needed. Offering approximately half a million square feet in a campus environment, this project will be quite special not only for Frederick, but for the entire region.”

Situated at the intersection of I-270 and I-70, the site is at the northern end of Maryland’s DNA Alley and part of the 2,000,000 sf Frederick life science cluster.  Proximate to Fort Detrick and the National Cancer Institute, as well as numerous private sector companies, Jefferson Technology Park will build upon the existing life science ecosystem to allow for continued and rapid growth of the life science industry in Frederick, MD.

Trammell Crow Company

Trammell Crow Company (TCC) is a global commercial real estate developer and wholly-owned subsidiary of CBRE Group, Inc. (NYSE:CBRE), a Fortune 500 and S&P 500 company headquartered in Dallas. Founded in 1948, TCC has developed or acquired nearly 2,900 buildings valued at $75 billion and over 655 million square feet. As of September 30, 2023, TCC had $15.4 billion of projects in process and $14.5 billion in its pipeline. It employs 650 professionals in 28 major cities throughout the United States and Europe. The company serves users of and investors in office, industrial/logistics, healthcare, life sciences and mixed-use projects, as well as multi-family residential through its operating subsidiary High Street Residential. For more information visit